Cohort profile: The International Childhood Cardiovascular Cohort (i3c) Consortium

Terence Dwyer, Cong Sun, Costan G. Magnussen, Olli T. Raitakari, Nicholas J. Schork, Alison Venn, Trudy L. Burns, Markus Juonala, Julia Steinberger, Alan R. Sinaiko, Ronald J. Prineas, Patricia H. Davis, Jessica G. Woo, John A. Morrison, Stephen R. Daniels, Wei Chen, Sathanur R. Srinivasan, Jorma S A Viikari, Gerald S. Berenson

Research output: Contribution to journalArticlepeer-review

91 Scopus citations


This is a consortium of large children's cohorts that contain measurements of major cardiovascular disease (CVD) risk factors in childhood and had the ability to follow those cohorts into adulthood. The purpose of this consortium is to enable the pooling of data to increase power, most importantly for the follow-up of CVD events in adulthood. Within the consortium, we hope to be able to obtain data on the independent effects of childhood and early adult levels of CVD risk factors on subsequent CVD occurrence.

Original languageEnglish (US)
Article numberdys004
Pages (from-to)86-96
Number of pages11
JournalInternational journal of epidemiology
Issue number1
StatePublished - Feb 2013

Bibliographical note

Funding Information:
The Muscatine Study was financially supported by National Institutes of Health (NIH) Grants (HL-14230) Specialized Center for Research in Atherosclerosis, (HL48050, HL-54730 and HL61857) from the National Heart, Lung, and Blood Institute, and (RR-00059) from the General Clinical Research Centers Program. The BHS was financially supported by NIH Grants (AG-16592) from the National Institute of Aging, (HL-38844) from the National Heart, Lung, and Blood Institute, and from the American Heart Association. The Cardiovascular Risk in Young Finns Study was financially supported by the Academy of Finland, the Social Insurance Institution of Finland, the Turku University Foundation, Special Federal Grants for the Turku, Tampere and Kuopio University Central Hospital, the Juho Vainio Foundation, Paavo Nurmi Foundation, the Finnish Foundation of Cardiovascular Research, Orion-Farmos Research Foundation and the Finnish Cultural Foundation. The CDAH Study was supported by the Commonwealth Departments of Sport, Recreation and Tourism, and Health; The National Heart Foundation; and the Commonwealth Schools Commission at baseline and the National Health and Medical Research Council, the Heart Foundation, the Tasmanian Community Fund and Veolia Environmental Services at follow-up. The National Health, Lung, and Blood Institute LRC Princeton Study and PFS were supported by NIH/ NHLBI (N01-HV-2-2914-L and HL62394), the American Heart Association (National-97 50129N) and NIH/NHLBI (R21DK085363). The Minneapolis Children’s studies were supported by NIH Grants (HL 52851, M01-RR-00400 and DK72124). The National Health, Lung, and Blood Institute Growth and Health Study was funded by NIH grants (HL52911, HC55025, HL66430 and HL48941). C.S. and C.G.M. are supported by the Australian National Health and Medical Research Council Early Career Public Health Fellowship (1013538 and 1037559, respectively). T.D. and C.S. are supported by the Victorian Government’s Operational Infrastructure Support Program.


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