Entrenamiento cognitivo en la esquizofrenia: Una aproximación basada en las neurociencias

Translated title of the contribution: Cognitive training in schizophrenia: A neuroscience-based approach

Alexander Genevsky, Coleman T. Garrett, Phillip P. Alexander, Sophia Vinogradov

Research output: Contribution to journalArticlepeer-review

43 Scopus citations

Abstract

Meta-analytic data from over a decade of research in cognitive remediation, when combined with recent findings from basic and clinical neuroscience, have resulted in a new understanding of the critical elements that can contribute to successful cognitive training approaches for schizophrenia. Some of these elements include: the use of computerized repetitive practice methods, high dosing schedules, a focus on sensory processing, and carefully constrained and individually adapted learning trials. In a preliminary randomized controlled trial of cognitive training exercises based on these principles, we demonstrated significant improvements in working memory, verbal learning and memory, and global cognition in patients with schizophrenia. These cognitive improvements were accompanied by neurobiological findings suggestive of learning-induced cortical plasticity. Future directions for research and essential remaining questions are discussed.

Translated title of the contributionCognitive training in schizophrenia: A neuroscience-based approach
Original languageSpanish
Pages (from-to)416-421
Number of pages6
JournalDialogues in Clinical Neuroscience
Volume12
Issue number3
StatePublished - Dec 9 2010

Keywords

  • Cognitive enhancement
  • Cognitive remediation
  • Cognitive training
  • Neuroplasticity
  • Schizophrenia

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