Cognitive disorders and brain MRI correlations in primary Sjögren's syndrome: Unlocking the secret of cognitive symptoms

Barbara M. Segal, Bryon A. Mueller

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations

Abstract

Little is known concerning the mechanisms of cognitive impairment in primary Sjögren's syndrome. However, recent technological advances have made detailed brain imaging studies possible, which have the potential to estimate more precisely the prevalence of CNS lesions in primary Sjögren's syndrome and to provide information on the severity and mechanisms of CNS tissue damage. Novel neuroimaging protocols can provide a window into cerebral organization that is not accessible with conventional imaging methods. Investigation of cognitive function with state of the art high-resolution structural and functional brain MRI could illuminate the mechanisms contributing to subtle cognitive dysfunction and guide the development of specific therapeutic approaches.

Original languageEnglish (US)
Pages (from-to)35-45
Number of pages11
JournalInternational Journal of Clinical Rheumatology
Volume6
Issue number1
DOIs
StatePublished - Feb 1 2011

Keywords

  • Sjögren's syndrome
  • brain MRI
  • cognitive disorders
  • mood

Fingerprint Dive into the research topics of 'Cognitive disorders and brain MRI correlations in primary Sjögren's syndrome: Unlocking the secret of cognitive symptoms'. Together they form a unique fingerprint.

Cite this