Cocaine hydrolase encoded in viral vector blocks the reinstatement of cocaine seeking in rats for 6 months

Keyphrases

• Viral Vectors 100%
• Cocaine Seeking 100%
• Cocaine Hydrolase 100%
• Cocaine 83%
• Amphetamine 50%
• Cocaine Dependence 33%
• Butyrylcholinesterase (BChE) 33%
• Gene Transfer 16%
• Cocaine-induced 16%
• Once-weekly 16%
• Intraperitoneal Injection 16%
• Viral Transfer 16%
• Female Rats 16%
• Albumin 16%
• Male Rats 16%
• Self-administration 16%
• Acid Hydrolysis 16%
• Self-administer 16%
• Fixed Ratio 16%
• Schedules of Reinforcement 16%
• Hydrolase Activity 16%
• Benzoic Acid 16%
• Lever Press 16%
• Direct Administration 16%
• Ecgonine Methyl Ester 16%
• Long-term Resistance 16%
• C(V) 16%
• Animal Model of Relapse 16%
• Pervasive Disorders 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Hydrolase 100%
• Viral Vector 100%
• Cocaine Dependence 33%
• Dexamphetamine 33%
• Cholinesterase 33%
• Table Salt 33%
• Intraperitoneal Injection 16%
• Ecgonine Methyl Ester 16%
• Disease 16%
• Gene Delivery 16%
• Benzoic Acid 16%

Neuroscience

• Hydrolase 100%
• Virus Vector 100%
• Cholinesterase 33%
• Cocaine Dependence 33%
• Intraperitoneal Injection 16%
• Gene Delivery 16%
• Ecgonine 16%
• Female Rats 16%
• Gene Transfer 16%
• Methyl Ester 16%
• Benzoic Acid 16%
• Blood Plasma 16%