Abstract
The metabolic state of T cells strongly influences their effector function and anti-tumor efficacy. St. Paul et al. (2021) report that Tc22, a CD8+ T cell subset with potent anti-tumor activity, upregulates the pantothenate/coenzyme A (CoA) pathway and that treatment with CoA or pantothenate is sufficient to enhance tumor immunotherapy.
Original language | English (US) |
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Pages (from-to) | 2305-2306 |
Number of pages | 2 |
Journal | Cell Metabolism |
Volume | 33 |
Issue number | 12 |
DOIs | |
State | Published - Dec 7 2021 |
Bibliographical note
Publisher Copyright:© 2021 Elsevier Inc.
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