TY - JOUR
T1 - Co-morbid traumatic brain injury and substance use disorder
T2 - Childhood predictors and adult correlates
AU - Felde, Anne B.
AU - Westermeyer, Joseph J
AU - Thuras, Paul
PY - 2006/1
Y1 - 2006/1
N2 - Primary objective: To examine demographic factors, childhood experiences and behaviour problems and adult psychopathology associated with a history of adult traumatic brain injury (TBI) with unconsciousness in patients with substance use disorders (SUD). Design and methods: Volunt ary patients (n=550) undergoing treatment for SUD were compared for clinical and demographic variables based on report of TBI. Results: Among the 218 (40%) patients reporting TBI, 61% were m en. Childhood conduct problems and loss of a parent were strongly associated with adult TBI. Patients with TBI had more severe SUD and higher rates of depressive and anxiety symptoms, somatic concerns, physical trauma, attempted suicide and Antisocial Personality Disorder. Conclusions: Men have a higher rate of TBI than women, but women with SUD have an increased relative risk of TBI compared to women in the general population. Childhood conduct problems and loss of a parent in childhood may predict adult risk-taking behaviour that leads to TBI in patients with SUD. TBI is associated with higher rates of psychopathology in patients with SUD.
AB - Primary objective: To examine demographic factors, childhood experiences and behaviour problems and adult psychopathology associated with a history of adult traumatic brain injury (TBI) with unconsciousness in patients with substance use disorders (SUD). Design and methods: Volunt ary patients (n=550) undergoing treatment for SUD were compared for clinical and demographic variables based on report of TBI. Results: Among the 218 (40%) patients reporting TBI, 61% were m en. Childhood conduct problems and loss of a parent were strongly associated with adult TBI. Patients with TBI had more severe SUD and higher rates of depressive and anxiety symptoms, somatic concerns, physical trauma, attempted suicide and Antisocial Personality Disorder. Conclusions: Men have a higher rate of TBI than women, but women with SUD have an increased relative risk of TBI compared to women in the general population. Childhood conduct problems and loss of a parent in childhood may predict adult risk-taking behaviour that leads to TBI in patients with SUD. TBI is associated with higher rates of psychopathology in patients with SUD.
KW - Antisocial personality disorder
KW - Comorbidity
KW - Conduct disorder
KW - Substance-related disorders
KW - Traumatic brain injury
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U2 - 10.1080/02699050500309718
DO - 10.1080/02699050500309718
M3 - Article
C2 - 16403699
AN - SCOPUS:31344433624
SN - 0883-041X
VL - 20
SP - 41
EP - 49
JO - Brain Injury
JF - Brain Injury
IS - 1
ER -