Abstract
Germfree rats were challenged orally and intrarectally with spores of Clostridium tetani. Although C. tetani spores remained viable in the intestinal tract, they were unable to germinate. Germfree rats were then challenged orally with vegetative cells of C. tetani. Vegetative cells were able to colonize the intestinal tract, replicate, and produce toxin. Tetanus antitoxin, but no tetanus toxin, was detected in the sera of monoassociated rats.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 826-828 |
| Number of pages | 3 |
| Journal | Infection and immunity |
| Volume | 41 |
| Issue number | 2 |
| DOIs | |
| State | Published - 1983 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
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