TY - JOUR
T1 - Clostridium tetani growth and toxin production in the intestines of germfree rats
AU - Wells, C. L.
AU - Balish, E.
PY - 1983
Y1 - 1983
N2 - Germfree rats were challenged orally and intrarectally with spores of Clostridium tetani. Although C. tetani spores remained viable in the intestinal tract, they were unable to germinate. Germfree rats were then challenged orally with vegetative cells of C. tetani. Vegetative cells were able to colonize the intestinal tract, replicate, and produce toxin. Tetanus antitoxin, but no tetanus toxin, was detected in the sera of monoassociated rats.
AB - Germfree rats were challenged orally and intrarectally with spores of Clostridium tetani. Although C. tetani spores remained viable in the intestinal tract, they were unable to germinate. Germfree rats were then challenged orally with vegetative cells of C. tetani. Vegetative cells were able to colonize the intestinal tract, replicate, and produce toxin. Tetanus antitoxin, but no tetanus toxin, was detected in the sera of monoassociated rats.
UR - http://www.scopus.com/inward/record.url?scp=0020577663&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0020577663&partnerID=8YFLogxK
U2 - 10.1128/iai.41.2.826-828.1983
DO - 10.1128/iai.41.2.826-828.1983
M3 - Article
C2 - 6347898
AN - SCOPUS:0020577663
SN - 0019-9567
VL - 41
SP - 826
EP - 828
JO - Infection and immunity
JF - Infection and immunity
IS - 2
ER -
