Clonal expansion of antigen-specific CD4 T cells following infection with Salmonella typhimurium is similar in susceptible (Ity(s)) and resistant (Ity(r)) BALB/c mice

Zong Ming Chen; Marc Jenkins

doi:10.1128/.67.4.2025-2029.1999

Clonal expansion of antigen-specific CD4 T cells following infection with Salmonella typhimurium is similar in susceptible (Ity(s)) and resistant (Ity(r)) BALB/c mice

Zong Ming Chen, Marc Jenkins

Microbiology

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

The results show that CD4 T cells specific for a recombinant antigen expressed in Salmonella typhimurium proliferate normally in mice that express the susceptible form of the Ity gene at early times after infection but do not retain the capacity to produce gamma interferon later in the infection.

Original language	English (US)
Pages (from-to)	2025-2029
Number of pages	5
Journal	Infection and immunity
Volume	67
Issue number	4
DOIs	https://doi.org/10.1128/.67.4.2025-2029.1999
State	Published - 1999

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title = "Clonal expansion of antigen-specific CD4 T cells following infection with Salmonella typhimurium is similar in susceptible (Ity(s)) and resistant (Ity(r)) BALB/c mice",

abstract = "The results show that CD4 T cells specific for a recombinant antigen expressed in Salmonella typhimurium proliferate normally in mice that express the susceptible form of the Ity gene at early times after infection but do not retain the capacity to produce gamma interferon later in the infection.",

author = "Chen, {Zong Ming} and Marc Jenkins",

year = "1999",

doi = "10.1128/.67.4.2025-2029.1999",

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AU - Jenkins, Marc

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N2 - The results show that CD4 T cells specific for a recombinant antigen expressed in Salmonella typhimurium proliferate normally in mice that express the susceptible form of the Ity gene at early times after infection but do not retain the capacity to produce gamma interferon later in the infection.

AB - The results show that CD4 T cells specific for a recombinant antigen expressed in Salmonella typhimurium proliferate normally in mice that express the susceptible form of the Ity gene at early times after infection but do not retain the capacity to produce gamma interferon later in the infection.

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M3 - Article

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AN - SCOPUS:0033068115

SN - 0019-9567

VL - 67

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JO - Infection and Immunity

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ER -

Clonal expansion of antigen-specific CD4 T cells following infection with Salmonella typhimurium is similar in susceptible (Ity(s)) and resistant (Ity(r)) BALB/c mice

Abstract

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