Clinical results of implant placement in resorbed ridges using simultaneous guided bone regeneration: a multicenter case series

Ioannis Konstantinidis, Tarun Kumar, Udatta Kher, Panagiotis D. Stanitsas, James E. Hinrichs, Georgios A. Kotsakis

Research output: Contribution to journalArticlepeer-review

24 Scopus citations


Materials and methods: Implants were placed in patients exhibiting Seibert class I ridge defects resulting in peri-implant dehiscence defects. The defects were treated following GBR principles with the use of a CPS alloplastic bone graft putty in combination either with a collagen membrane or a titanium mesh. The height of each bony dehiscence was clinically measured at the time of implant placement and again during second-stage surgery. The percentage of complete defect coverage, frequency of adverse events, and risk factors for residual defect were determined.

Results: Thirty-six implants were placed in 26 patients. Twenty-seven of the 36 sites employed a collagen membrane in conjunction with the CPS while the remaining nine sites utilized a titanium membrane. Mean gain in bone height was 3.23 ± 2.04 mm, with 75 % of the peri-implant defects achieving complete regeneration. A negative correlation was identified between patient age and complete coverage of the peri-implant defect (p = 0.026). The implant survival rate at 12 months was 97.22 %.

Conclusion: Use of CPS bone putty during delayed implant placement at peri-implant dehiscence sites either in combination with a collagen membrane or a titanium mesh results in predictable defect coverage.

Objectives: The purpose of this case series was to evaluate the new bone formation following guided bone regeneration (GBR) with a calcium phosphosilicate (CPS), alloplastic bone putty at peri-implant dehiscence defects and to assess survival rate of implants placed in the augmented sites after 12 months of function.

Clinical relevance: The handling characteristics of CPS putty may simplify GBR protocol. Implants placed in conjunction with GBR have a very good survival rate after 1 year of follow-up.

Original languageEnglish (US)
Pages (from-to)553-559
Number of pages7
JournalClinical oral investigations
Issue number2
StatePublished - Mar 2015

Bibliographical note

Publisher Copyright:
© 2014, Springer-Verlag Berlin Heidelberg.


  • Alloplastic bone putty
  • Calcium phosphosilicate (CPS)
  • Guided bone regeneration (GBR)
  • Peri-implant dehiscence defects


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