Clinical remission following plasmapheresis and corticosteroid treatment in a dog with acquired myasthenia gravis.

J. W. Bartges, J. S. Klausner, E. F. Bostwick, J. E. Hakala, V. A. Lennon

Research output: Contribution to journalArticle

25 Scopus citations

Abstract

A 7-year-old sexually intact male Labrador Retriever with regurgitation and generalized muscular weakness resulting from acquired myasthenia gravis received 2 plasmapheresis treatments in combination with corticosteroid treatment. Plasmapheresis was performed in an attempt to rapidly lower serum acetylcholine receptor binding antibody (AChR Ab) concentration. Seven days after the second plasmapheresis treatment, the dog's muscular strength was normal, which coincided with a 70% decrease in serum AChR Ab concentration. Because the dog also received corticosteroids, it is impossible to determine how much of the clinical improvement resulted from plasmapheresis.

Original languageEnglish (US)
Pages (from-to)1276-1278
Number of pages3
JournalJournal of the American Veterinary Medical Association
Volume196
Issue number8
StatePublished - Apr 15 1990

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