TY - JOUR
T1 - Clinical, radiographic, histologic, and histomorphometric comparison of pepgen p-15 particulate and pepgen p-15 flow in extraction sockets
T2 - A same-mouth case study
AU - Hahn, Jack
AU - Rohrer, Michael D.
AU - Tofe, Andrew J.
PY - 2003
Y1 - 2003
N2 - Purpose Although the efficacy of PepGen P-15 particulate has been conclusively demonstrated in two multicenter clinical studies, the effect of a new hydrogel formulation containing PepGen P-15 on bone repair has not been previously demonstrated. Materials and Methods PepGen P-15 Flow contains PepGen P-15 particulate in a biocompatible hydrogel, which provides spacing between the particles. In this case study, bone repair of both PepGen P-15 particles and PepGen P-15 Flow was compared to natural bone in same-mouth extraction sockets. Results The radiographic, histologic, and histomorphometric evaluations showed enhanced bone formation and faster particle resorption with PepGen P-15 Flow compared to the PepGen P-15 particulate. Conclusion The accelerated bone formation by PepGen P-15 Flow may provide faster implant placement.
AB - Purpose Although the efficacy of PepGen P-15 particulate has been conclusively demonstrated in two multicenter clinical studies, the effect of a new hydrogel formulation containing PepGen P-15 on bone repair has not been previously demonstrated. Materials and Methods PepGen P-15 Flow contains PepGen P-15 particulate in a biocompatible hydrogel, which provides spacing between the particles. In this case study, bone repair of both PepGen P-15 particles and PepGen P-15 Flow was compared to natural bone in same-mouth extraction sockets. Results The radiographic, histologic, and histomorphometric evaluations showed enhanced bone formation and faster particle resorption with PepGen P-15 Flow compared to the PepGen P-15 particulate. Conclusion The accelerated bone formation by PepGen P-15 Flow may provide faster implant placement.
KW - Anorganic bone mineral
KW - Enhanced bone regeneration
KW - Hydrogel
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U2 - 10.1097/01.ID.0000064812.39660.FF
DO - 10.1097/01.ID.0000064812.39660.FF
M3 - Article
C2 - 12861886
AN - SCOPUS:0042888885
VL - 12
SP - 170
EP - 174
JO - The International journal of oral implantology : implantologist
JF - The International journal of oral implantology : implantologist
SN - 1056-6163
IS - 2
ER -