Clinical Profile of Patients With Unilateral Sudden Sensorineural Hearing Loss: Correlation With Hearing Prognosis

Adriana Perez Ferreira Neto, Rafael da Costa Monsanto, Line Dore Saint Jean, Lucas Sonzzini Ribeiro de Souza, Norma de Oliveira Penido

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: To characterize, with a standard systematic protocol, the clinical and audiometric profile of patients with idiopathic sudden sensorineural hearing loss (ISSNHL) and to correlate the findings with hearing recovery prognosis. Study Design: Retrospective cohort of patients with ISSNHL. Setting: Outpatients of a tertiary referral center followed for 20 years. Methods: We collected clinical information, including the presence of tinnitus, vertigo, and comorbidities, as well as initial pure tone averages, degree of hearing loss, audiogram curves, and time between hearing loss onset and treatment. These variables were statistically analyzed for their impact on hearing recovery prognosis. All patients were treated with oral corticosteroids, following a standard treatment protocol. Hearing recovery was defined according to the criteria of the American Academy of Otolaryngology–Head and Neck Surgery Foundation, and hearing outcomes were reported via a standardized method (scattergrams). Results: Our final study group comprised 186 patients. Most patients were between 41 and 60 years of age. Univariate analysis revealed that vertigo; presence of severe or profound initial hearing loss; flat, U-shaped, and descending audiogram curves; and initiating treatment ≥15 days were correlated with worse hearing recovery. However, the multivariate logistic model revealed that only the presence of severe or profound hearing loss (odds ratio, 6.634; 95% CI, 2.714-16.216; P <.001) and initiating treatment ≥15 days (odds ratio, 0.250; 95% CI, 0.102-0.610; P =.008) were independent risk factors for worse hearing recovery prognosis. Conclusion: This study demonstrated that the presence of severe or profound hearing loss at the first audiogram and initiating treatment after 14 days from ISSNHL onset were independent risk factors associated with a worse hearing recovery prognosis.

Original languageEnglish (US)
Pages (from-to)563-570
Number of pages8
JournalOtolaryngology - Head and Neck Surgery (United States)
Volume165
Issue number4
DOIs
StatePublished - Oct 2021
Externally publishedYes

Bibliographical note

Funding Information:
We acknowledge Gianni Mara Silva dos Santos for the statistical analysis.

Publisher Copyright:
© American Academy of Otolaryngology–Head and Neck Surgery Foundation 2021.

Keywords

  • audiometry
  • clinical profile
  • prognosis
  • sudden sensorineural hearing loss

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