Clinical practice guideline for emergency department ketamine dissociative sedation: 2011 update

Steven M. Green, Mark G. Roback, Robert M. Kennedy, Baruch Krauss

Research output: Contribution to journalArticlepeer-review

300 Scopus citations

Abstract

We update an evidence-based clinical practice guideline for the administration of the dissociative agent ketamine for emergency department procedural sedation and analgesia. Substantial new research warrants revision of the widely disseminated 2004 guideline, particularly with respect to contraindications, age recommendations, potential neurotoxicity, and the role of coadministered anticholinergics and benzodiazepines. We critically discuss indications, contraindications, personnel requirements, monitoring, dosing, coadministered medications, recovery issues, and future research questions for ketamine dissociative sedation.

Original languageEnglish (US)
Pages (from-to)449-461
Number of pages13
JournalAnnals of Emergency Medicine
Volume57
Issue number5
DOIs
StatePublished - May 2011

Bibliographical note

Copyright:
Copyright 2011 Elsevier B.V., All rights reserved.

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