Clinical Experience with Toxic-Shock Syndrome

Robert W. Tofte, Kent B. Crossley, David N. Williams

Research output: Contribution to journalLetterpeer-review

5 Scopus citations


To the Editor: We have recently treated 16 patients (14 female and two male) with toxic-shock syndrome. Since there is a dearth of medical literature on this disease, we think that a brief description of the illness and its association with Staphylococcus aureus would be beneficial to the practitioner. Toxic-shock syndrome, originally described by Todd et al., 1 is an uncommon illness that occurs primarily in previously healthy women, with onset during the second to fourth days of menstruation.2 , 3 It is characterized clinically by the abrupt onset of fever above 38.9°C (102°F), mild headache, sore throat, profound lethargy, intermittent confusion, nausea,.

Original languageEnglish (US)
Number of pages1
JournalNew England Journal of Medicine
Issue number24
StatePublished - Dec 11 1980

Fingerprint Dive into the research topics of 'Clinical Experience with Toxic-Shock Syndrome'. Together they form a unique fingerprint.

Cite this