Clinical characterization of canine acanthomatous ameloblastoma (CAA) in 263 dogs and the influence of postsurgical histopathological margin on local recurrence

Stephanie L. Goldschmidt, Cindy M. Bell, Scott Hetzel, Jason Soukup

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Canine acanthomatous ameloblastoma (CAA) has been reported to be the most common odontogenic tumor in dogs. This retrospective study evaluated 263 dogs with histopathologically confirmed CAA. Within this data set, CAA presents most commonly in the rostral mandible in adult large breed dogs, with golden retriever dogs being overrepresented. Patients with appropriate follow-up after curative intent surgery were evaluated to assess the effect of histopathological margin on local tumor recurrence. No local recurrence was noted in any patient. This study raises questions about what the recommended surgical margin should be for treatment of CAA. It also serves as a stimulus for discussion as to whether further treatment for CAA is required when inadequate surgical margins are obtained, or if medical surveillance would be an appropriate management recommendation. Prospective studies are necessary to answer these questions.

Original languageEnglish (US)
Pages (from-to)241-247
Number of pages7
JournalJournal of Veterinary Dentistry
Volume34
Issue number4
DOIs
StatePublished - Dec 2017

Bibliographical note

Funding Information:
The author(s) disclosed the following financial support for the research, authorship, and/or publication of this article: This project was supported by the Clinical and Translational Science Award (CTSA) program, through the NIH National Center for Advancing Translational Sciences (NCATS), grant UL1TR000427. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH.

Keywords

  • CAA
  • Canine acanthomatous ameloblastoma
  • Dog
  • Histological margin
  • Local recurrence CAA
  • Odontogenic tumors

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