Clinical Application of Body Composition Methods in Premature Infants.

Emily M Nagel, Marie K Hickey, Levi M Teigen, Adam Kuchnia, Kent Curran, Lisa Soumekh, Carrie P Earthman, Ellen W. Demerath, Sara E Ramel

Research output: Contribution to journalReview articlepeer-review

14 Scopus citations


Monitoring whole body composition (fat mass and fat-free mass) in preterm infants may assist in optimizing nutrition and promoting growth and neurodevelopment in the neonatal intensive care unit. Currently, body composition assessment is not part of routine clinical evaluation of premature infants. Instead, weight and length are used to assess growth but are known to be poor predictors of adiposity shortly after birth. Although body composition methods, such as magnetic resonance imaging, stable-isotope dilution, and dual-energy x-ray absorptiometry, have been examined in infants, they involve exposure to radiation and are invasive, expensive, and/or unsuitable for repeated measurements in a medically fragile population. Several body composition methods with potential for clinical use have been explored in premature infants, including air displacement plethysmography, bioimpedance, skinfold measurements, and ultrasound. In this review, we examine each method and evaluate its feasibility for incorporation into clinical care. Although these methods show promise for use in premature infants, further research is needed before they can be recommended for routine body composition assessment in the clinical setting.
Original languageEnglish (US)
Pages (from-to)785-795
Number of pages11
JournalJournal of Parenteral and Enteral Nutrition
Issue number5
Early online date2020
StatePublished - Jul 1 2020

Bibliographical note

Publisher Copyright:
© 2020 American Society for Parenteral and Enteral Nutrition


  • body composition
  • neonates
  • obesity

PubMed: MeSH publication types

  • Review
  • Journal Article


Dive into the research topics of 'Clinical Application of Body Composition Methods in Premature Infants.'. Together they form a unique fingerprint.

Cite this