Clinical angiographic regression of atherosclerosis after partial ileal bypass

Henry Buchwald; Richard B. Moore; Richard D. Rucker; Kurt Amplatz; Wilfredo R. Castaneda; Richard A. Francoz; Richard C. Pasternak; Richard L. Varco

doi:10.1016/0021-9150(83)90170-3

Clinical angiographic regression of atherosclerosis after partial ileal bypass

Henry Buchwald, Richard B. Moore, Richard D. Rucker, Kurt Amplatz, Wilfredo R. Castaneda, Richard A. Francoz, Richard C. Pasternak, Richard L. Varco

Surgery

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

Clinical documentation of atherosclerotic plaque regression has been difficult to obtain. This is a report of a patient with severe and early atherosclerotic cardiovascular disease with regression of at least three major atherosclerotic lesions demonstrated by coronary arteriography 10 years after partial ileal bypass operation. The patient's total plasma cholesterol was reduced over these 10 years, ranging from 40% to 23%, from the preoperative level of 757 mg/dl. Sequential arteriograms were assessed independently by several arteriographers and blindly by the Arteriography Review Panel of the Program on Surgical Control of the Hyperlipidemias (POSCH). The readings were analyzed by 4 grading methods. Unanimously, marked regression was read in the proximal left circumflex artery (70% → 20%), middle segment of the right coronary artery (45% → 20%), and in the distal right coronary artery (80% → 50%). Thus, by any and all of the methods used, there was significant regression of arteriographically demonstrated atherosclerotic lesions.

Original language	English (US)
Pages (from-to)	117-128
Number of pages	12
Journal	Atherosclerosis
Volume	46
Issue number	1
DOIs	https://doi.org/10.1016/0021-9150(83)90170-3
State	Published - Jan 1983

Bibliographical note

Funding Information:
Supported by a grant from the National Heart, Lung. and Bloed Institute, HL-1 1901. and a Special Legislative Grant from the State of Minnesota. * Program on Surgical Control of the Hyperlipidemias (POSCH) Arteriography Review Panel: David Blankenhom, MD, Kurt Amplatz, MD. Joseph Bissett, MD, Wilfrido Castaneda, MD. MalcoIm Pearce. MD, Miguel Sanmarco, MD, Harry Sawin, MD. Reprint requests to: Henry Buchwald, MD, PhD, University of Minnesota Hospitals, Box 290 - Mayo, Minneapolis, MN 55455, U.S.A.

Keywords

Atherosclerotic lesion regression - Coronary arteriography - Partial ileal bypass - Plasma cholesterol and cholesterol fractions - POSCH Arteriography Review Panel

UN SDGs

This output contributes to the following Sustainable Development Goal(s)

Access

10.1016/0021-9150(83)90170-3

Fingerprint Dive into the research topics of 'Clinical angiographic regression of atherosclerosis after partial ileal bypass'. Together they form a unique fingerprint.

Cite this

@article{f7b8fad3a9ab4dba97c4686ad61761d6,

title = "Clinical angiographic regression of atherosclerosis after partial ileal bypass",

abstract = "Clinical documentation of atherosclerotic plaque regression has been difficult to obtain. This is a report of a patient with severe and early atherosclerotic cardiovascular disease with regression of at least three major atherosclerotic lesions demonstrated by coronary arteriography 10 years after partial ileal bypass operation. The patient's total plasma cholesterol was reduced over these 10 years, ranging from 40% to 23%, from the preoperative level of 757 mg/dl. Sequential arteriograms were assessed independently by several arteriographers and blindly by the Arteriography Review Panel of the Program on Surgical Control of the Hyperlipidemias (POSCH). The readings were analyzed by 4 grading methods. Unanimously, marked regression was read in the proximal left circumflex artery (70% → 20%), middle segment of the right coronary artery (45% → 20%), and in the distal right coronary artery (80% → 50%). Thus, by any and all of the methods used, there was significant regression of arteriographically demonstrated atherosclerotic lesions.",

keywords = "Atherosclerotic lesion regression - Coronary arteriography - Partial ileal bypass - Plasma cholesterol and cholesterol fractions - POSCH Arteriography Review Panel",

author = "Henry Buchwald and Moore, {Richard B.} and Rucker, {Richard D.} and Kurt Amplatz and Castaneda, {Wilfredo R.} and Francoz, {Richard A.} and Pasternak, {Richard C.} and Varco, {Richard L.}",

note = "Funding Information: Supported by a grant from the National Heart, Lung. and Bloed Institute, HL-1 1901. and a Special Legislative Grant from the State of Minnesota. * Program on Surgical Control of the Hyperlipidemias (POSCH) Arteriography Review Panel: David Blankenhom, MD, Kurt Amplatz, MD. Joseph Bissett, MD, Wilfrido Castaneda, MD. MalcoIm Pearce. MD, Miguel Sanmarco, MD, Harry Sawin, MD. Reprint requests to: Henry Buchwald, MD, PhD, University of Minnesota Hospitals, Box 290 - Mayo, Minneapolis, MN 55455, U.S.A.",

year = "1983",

month = jan,

doi = "10.1016/0021-9150(83)90170-3",

language = "English (US)",

volume = "46",

pages = "117--128",

journal = "Atherosclerosis",

issn = "0021-9150",

publisher = "Elsevier Ireland Ltd",

number = "1",

}

TY - JOUR

T1 - Clinical angiographic regression of atherosclerosis after partial ileal bypass

AU - Buchwald, Henry

AU - Moore, Richard B.

AU - Rucker, Richard D.

AU - Amplatz, Kurt

AU - Castaneda, Wilfredo R.

AU - Francoz, Richard A.

AU - Pasternak, Richard C.

AU - Varco, Richard L.

N1 - Funding Information: Supported by a grant from the National Heart, Lung. and Bloed Institute, HL-1 1901. and a Special Legislative Grant from the State of Minnesota. * Program on Surgical Control of the Hyperlipidemias (POSCH) Arteriography Review Panel: David Blankenhom, MD, Kurt Amplatz, MD. Joseph Bissett, MD, Wilfrido Castaneda, MD. MalcoIm Pearce. MD, Miguel Sanmarco, MD, Harry Sawin, MD. Reprint requests to: Henry Buchwald, MD, PhD, University of Minnesota Hospitals, Box 290 - Mayo, Minneapolis, MN 55455, U.S.A.

PY - 1983/1

Y1 - 1983/1

N2 - Clinical documentation of atherosclerotic plaque regression has been difficult to obtain. This is a report of a patient with severe and early atherosclerotic cardiovascular disease with regression of at least three major atherosclerotic lesions demonstrated by coronary arteriography 10 years after partial ileal bypass operation. The patient's total plasma cholesterol was reduced over these 10 years, ranging from 40% to 23%, from the preoperative level of 757 mg/dl. Sequential arteriograms were assessed independently by several arteriographers and blindly by the Arteriography Review Panel of the Program on Surgical Control of the Hyperlipidemias (POSCH). The readings were analyzed by 4 grading methods. Unanimously, marked regression was read in the proximal left circumflex artery (70% → 20%), middle segment of the right coronary artery (45% → 20%), and in the distal right coronary artery (80% → 50%). Thus, by any and all of the methods used, there was significant regression of arteriographically demonstrated atherosclerotic lesions.

AB - Clinical documentation of atherosclerotic plaque regression has been difficult to obtain. This is a report of a patient with severe and early atherosclerotic cardiovascular disease with regression of at least three major atherosclerotic lesions demonstrated by coronary arteriography 10 years after partial ileal bypass operation. The patient's total plasma cholesterol was reduced over these 10 years, ranging from 40% to 23%, from the preoperative level of 757 mg/dl. Sequential arteriograms were assessed independently by several arteriographers and blindly by the Arteriography Review Panel of the Program on Surgical Control of the Hyperlipidemias (POSCH). The readings were analyzed by 4 grading methods. Unanimously, marked regression was read in the proximal left circumflex artery (70% → 20%), middle segment of the right coronary artery (45% → 20%), and in the distal right coronary artery (80% → 50%). Thus, by any and all of the methods used, there was significant regression of arteriographically demonstrated atherosclerotic lesions.

KW - Atherosclerotic lesion regression - Coronary arteriography - Partial ileal bypass - Plasma cholesterol and cholesterol fractions - POSCH Arteriography Review Panel

UR - http://www.scopus.com/inward/record.url?scp=0020659066&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020659066&partnerID=8YFLogxK

U2 - 10.1016/0021-9150(83)90170-3

DO - 10.1016/0021-9150(83)90170-3

M3 - Article

C2 - 6838688

AN - SCOPUS:0020659066

VL - 46

SP - 117

EP - 128

JO - Atherosclerosis

JF - Atherosclerosis

SN - 0021-9150

IS - 1

ER -

Clinical angiographic regression of atherosclerosis after partial ileal bypass

Abstract

Bibliographical note

Keywords

UN SDGs

Access

Other files and links

Cite this