Cleavage of phospholipase D1 by caspase promotes apoptosis via modulation of the p53-dependent cell death pathway

Keyphrases

• Cell Death Pathways 100%
• Caspase 100%
• P53-dependent Cell Death 100%
• Phospholipase D1 (PLD1) 100%
• Promote Apoptosis 100%
• Apoptosis 23%
• Enzymatic Activity 11%
• Induced Apoptosis 5%
• Small Interfering RNA (siRNA) 5%
• Apoptotic Pathway 5%
• Cell Survival 5%
• P53 Pathway 5%
• P53-dependent Apoptosis 5%
• Mutant Forms 5%
• Amino Acid Sequence 5%
• C-terminal Fragments 5%
• Phospholipase D 5%
• Significant Level 5%
• P53-independent 5%
• Resistant mutants 5%
• Dominant Negative Effect 5%
• N-terminal Fragment 5%
• Phospholipase D Activity 5%
• Cell Protection 5%
• ATM-Chk2 5%
• Small Fraction 5%

Biochemistry, Genetics and Molecular Biology

• Cell Death 100%
• P53 100%
• Caspase 100%
• Phospholipase D1 100%
• Enzyme Activity 33%
• Phospholipase D 33%
• RNA 16%
• Wild Type 16%
• Cell Protection 16%
• N-Terminus 16%
• Peptide Sequence 16%
• Cell Survival 16%
• C-Terminus 16%