Citrifolinin A, a new unusual iridoid with inhibition of Activator Protein-1 (AP-1) from the leaves of noni (Morinda citrifolia L.)

Shengmin Sang; Kan He; Guangming Liu; Nanqun Zhu; Mingfu Wang; Jin Woo Jhoo; Qunyi Zheng; Zigang Dong; Geetha Ghai; Robert T. Rosen; Chi Tang Ho

doi:10.1016/S0040-4039(01)00018-1

Citrifolinin A, a new unusual iridoid with inhibition of Activator Protein-1 (AP-1) from the leaves of noni (Morinda citrifolia L.)

Shengmin Sang, Kan He, Guangming Liu, Nanqun Zhu, Mingfu Wang, Jin Woo Jhoo, Qunyi Zheng, Zigang Dong, Geetha Ghai, Robert T. Rosen, Chi Tang Ho

The Hormel Institute

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

A new unusual iridoid, named citrifolinin A, showing significant inhibition of UVB-induced Activator Protein-1 (AP-1) activity in cell cultures, has been isolated from the leaves of Morinda citrifolia. Its structure was elucidated based on a detailed high-field 1D and 2D spectral analysis.

Original language	English (US)
Pages (from-to)	1823-1825
Number of pages	3
Journal	Tetrahedron Letters
Volume	42
Issue number	10
DOIs	https://doi.org/10.1016/S0040-4039(01)00018-1
State	Published - Mar 4 2001

Keywords

AP-1
Citrifolinin A
Iridoid
Morinda citrifolia L.
Noni

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10.1016/S0040-4039(01)00018-1

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title = "Citrifolinin A, a new unusual iridoid with inhibition of Activator Protein-1 (AP-1) from the leaves of noni (Morinda citrifolia L.)",

abstract = "A new unusual iridoid, named citrifolinin A, showing significant inhibition of UVB-induced Activator Protein-1 (AP-1) activity in cell cultures, has been isolated from the leaves of Morinda citrifolia. Its structure was elucidated based on a detailed high-field 1D and 2D spectral analysis.",

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author = "Shengmin Sang and Kan He and Guangming Liu and Nanqun Zhu and Mingfu Wang and Jhoo, {Jin Woo} and Qunyi Zheng and Zigang Dong and Geetha Ghai and Rosen, {Robert T.} and Ho, {Chi Tang}",

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doi = "10.1016/S0040-4039(01)00018-1",

language = "English (US)",

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T1 - Citrifolinin A, a new unusual iridoid with inhibition of Activator Protein-1 (AP-1) from the leaves of noni (Morinda citrifolia L.)

AU - Sang, Shengmin

AU - He, Kan

AU - Liu, Guangming

AU - Zhu, Nanqun

AU - Wang, Mingfu

AU - Jhoo, Jin Woo

AU - Zheng, Qunyi

AU - Dong, Zigang

AU - Ghai, Geetha

AU - Rosen, Robert T.

AU - Ho, Chi Tang

PY - 2001/3/4

Y1 - 2001/3/4

N2 - A new unusual iridoid, named citrifolinin A, showing significant inhibition of UVB-induced Activator Protein-1 (AP-1) activity in cell cultures, has been isolated from the leaves of Morinda citrifolia. Its structure was elucidated based on a detailed high-field 1D and 2D spectral analysis.

AB - A new unusual iridoid, named citrifolinin A, showing significant inhibition of UVB-induced Activator Protein-1 (AP-1) activity in cell cultures, has been isolated from the leaves of Morinda citrifolia. Its structure was elucidated based on a detailed high-field 1D and 2D spectral analysis.

KW - AP-1

KW - Citrifolinin A

KW - Iridoid

KW - Morinda citrifolia L.

KW - Noni

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U2 - 10.1016/S0040-4039(01)00018-1

DO - 10.1016/S0040-4039(01)00018-1

M3 - Article

AN - SCOPUS:0035804474

SN - 0040-4039

VL - 42

SP - 1823

EP - 1825

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 10

ER -

Citrifolinin A, a new unusual iridoid with inhibition of Activator Protein-1 (AP-1) from the leaves of noni (Morinda citrifolia L.)

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