Circadian urinary glucocorticoid and rhythmic blood pressure coordination

M. J. Halhuber, Germaine G Cornelissen-Guillaume, F. C. Bartter, C. S. Delea, A. Kreze, M. Mikulecky, T. Müller-Bohn, J. Siegelová, J. Dušek, O. Schwartzkopff, F. Halberg

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Circadian variations in urinary 17-hydroxycorticosteroids (17-OHCS) and blood pressure were examined in patients (n=42) with MESOR-hypotension, MESOR-normotension and MESOR-hypertension with no known endocrine disorder. Relations were sought between adrenocortical function and blood pressure. All data were evaluated using the Halberg cosinor analysis. In this study, in a separate group of patients (n=21), life expectancy was also examined as a function of the circadian blood pressure amplitude.

Original languageEnglish (US)
Pages (from-to)139-144
Number of pages6
JournalScripta Medica Facultatis Medicae Universitatis Brunensis Masarykianae
Issue number3
StatePublished - 2002


  • Blood pressure
  • Circadian rhythm
  • Urinary glucocorticoid


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