Circadian rhythms and circadian rhythm disorders in children and Adolescents

John Garcia, Gerald Rosen, Mark Mahowald

Research output: Contribution to journalArticlepeer-review

48 Scopus citations


A clinically applicable review of circadian rhythm physiology is presented, including a detailed examination of the interaction of circadian and homeostatic systems and the maturation of the circadian system from preconception through adolescence. Emphasis is placed on the clinical evaluation gathering information through the history, sleep log, and if necessary, actigraphy and polysomnography. Circadian disorders, including advanced sleep phase syndrome, circadian disorders seen in blind children, delayed sleep phase syndrome, and non-24-hour sleep phase are described. Case descriptions of each are provided. Treatment and interventions for these disorders are described, including the importance of education, light therapy, sleep-wake schedule adjustments, and the occasional use of medications, such as sedative hypnotics and melatonin.

Original languageEnglish (US)
Pages (from-to)229-240
Number of pages12
JournalSeminars in Pediatric Neurology
Issue number4
StatePublished - 2001

Bibliographical note

Funding Information:
From the Minnesota Regional Sleep Disorder Center, Hen-nepin County Medical Center, Minneapolis, MN. The preparation of this article was supported in part by the National Institutes of Health Heart, Lung and Blood Grant #K07 HL03890-01. Address reprint requests to John Garcia, MD, Sleep Disorders Center, Hennepin County Medical Center, 701 Park Ave South, Minneapolis, MN 55415. ColO'right 9 2001 by W.B. Saunders Company 1071-9091/01,0804-0006535.00/0 doi..10.1053/sperL2001.29044


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