Circadian reference values for different endpoints of heart rate variability

Kuniaki Otsuka, Germaine G Cornelissen-Guillaume, M. Shinagawa, Y. Nishimura, Y. Kubo, N. Hotta, C. Fujii, T. Ishii, K. Omori, Y. Watanabe, S. Nunoda, S. Ohkawa, F. Halberg

Research output: Contribution to journalConference article

4 Citations (Scopus)

Abstract

While it is known that endpoints of HRV undergo a circadian variation, time-specified reference value ranges are lacking. To fill this void, peer-group reference standards are presented. They are derived on the basis of data from 219 healthy males in 8 age groups: 5-10 years, 10-20 years, 20-30 years, 30-40 years, 40-50 years, 50-60 years, 60-70 years and >70 years, and from 117 healthy females in 4 age groups: <20 years, 20-40 years, 40-60 years, and >60 years. The spectral Q component (Q for quadrisecundan, rather than `HF') and the D/Q ratio (D for decisecundan, rather than `LF/HF') were computed hourly for 24 hours. Time-specified reference limits (chronodesms) were computed for each variable in each group as 90% prediction limits. Circadian chronodesms in different age groups indicate that both Q and D/Q vary greatly as a function of age. Chronodesms here proposed may serve for evaluating risk and the efficacy of various interventions.

Original languageEnglish (US)
Pages (from-to)587-590
Number of pages4
JournalComputers in Cardiology
StatePublished - Dec 1 1999
EventThe 26th Annual Meeting: Computers in Cardiology 1999 - Hannover, Ger
Duration: Sep 26 1999Sep 29 1999

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Reference Values
Age Groups
Heart Rate
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Otsuka, K., Cornelissen-Guillaume, G. G., Shinagawa, M., Nishimura, Y., Kubo, Y., Hotta, N., ... Halberg, F. (1999). Circadian reference values for different endpoints of heart rate variability. Computers in Cardiology, 587-590.

Circadian reference values for different endpoints of heart rate variability. / Otsuka, Kuniaki; Cornelissen-Guillaume, Germaine G; Shinagawa, M.; Nishimura, Y.; Kubo, Y.; Hotta, N.; Fujii, C.; Ishii, T.; Omori, K.; Watanabe, Y.; Nunoda, S.; Ohkawa, S.; Halberg, F.

In: Computers in Cardiology, 01.12.1999, p. 587-590.

Research output: Contribution to journalConference article

Otsuka, K, Cornelissen-Guillaume, GG, Shinagawa, M, Nishimura, Y, Kubo, Y, Hotta, N, Fujii, C, Ishii, T, Omori, K, Watanabe, Y, Nunoda, S, Ohkawa, S & Halberg, F 1999, 'Circadian reference values for different endpoints of heart rate variability', Computers in Cardiology, pp. 587-590.
Otsuka, Kuniaki ; Cornelissen-Guillaume, Germaine G ; Shinagawa, M. ; Nishimura, Y. ; Kubo, Y. ; Hotta, N. ; Fujii, C. ; Ishii, T. ; Omori, K. ; Watanabe, Y. ; Nunoda, S. ; Ohkawa, S. ; Halberg, F. / Circadian reference values for different endpoints of heart rate variability. In: Computers in Cardiology. 1999 ; pp. 587-590.
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