Circadian blood pressure variability in healthy pregnancy and women with gestational hypertension

D. E. Ayala, R. C. Hermida, A. Mojon, M. Iglesias, G. Cornelissen, F. Halberg

Research output: Contribution to journalConference articlepeer-review

2 Scopus citations


The assessment of anticipated variability in blood pressure and heart rate by utilizing fully ambulatory devices and the appropriate processing of the time series secured, can be beneficial in examining early cardiovascular disease risk in pregnant women. A total of 193 pregnant women furnished 301 blood pressure data taken every hour for 48 hours with an ambulatory device. The circadian variables of blood pressure were computed on the outset for every profile of measurement, using the least-squares fit of a 24-hour cosine curve, and then applied in circadian rhythm characteristics assessment for both the uncomplicated group and the complicated group. Based on the consequences, a significant increase of blood pressure was found in pregnancies with gestational hypertension or preeclampsia in all trimesters of pregnancy. However, these variances took place within systolic and diastolic blood pressure values within the present acceptable scope of physiological variation.

Original languageEnglish (US)
Pages (from-to)287-292
Number of pages6
JournalProceedings of the IEEE Symposium on Computer-Based Medical Systems
StatePublished - Dec 1 1994
EventProceedings of the 1994 IEEE 7th Symposium on Computer-Based Medical Systems - Winston-Salem, NC, USA
Duration: Jun 11 1994Jun 12 1994


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