Circadian and circaseptan dependence of the beta-ATP peak of four different cancer cell cultures: Implications for chronoradiotherapy

W. Ulmer; G. Cornelissen; M. Revilla; J. Siegelová; J. Dušek; F. Halberg

Circadian and circaseptan dependence of the beta-ATP peak of four different cancer cell cultures: Implications for chronoradiotherapy

W. Ulmer
, G. Cornelissen
, M. Revilla
, J. Siegelová
, J. Dušek
, F. Halberg

Integrative Biology and Physiology

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

The aim of the study was to examine the time-dependence of the beta-ATP peak of different tumor cells in vitro as a gauge of overall metabolism. In view of the large circaseptan-over-circadian prominence of the time-dependence of the beta-ATP peak, it is suggested to modulate the administration of radiotherapy according to a weekly schedule, to optimize treatment efficacy.

Original language	English (US)
Pages (from-to)	87-92
Number of pages	6
Journal	Scripta Medica Facultatis Medicae Universitatis Brunensis Masarykianae
Volume	74
Issue number	2
State	Published - 2001

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Beta-ATP peak
Cancer cell cultures
Circadian and circaseptan rhythm
Implications for chronoradiotherapy

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title = "Circadian and circaseptan dependence of the beta-ATP peak of four different cancer cell cultures: Implications for chronoradiotherapy",

abstract = "The aim of the study was to examine the time-dependence of the beta-ATP peak of different tumor cells in vitro as a gauge of overall metabolism. In view of the large circaseptan-over-circadian prominence of the time-dependence of the beta-ATP peak, it is suggested to modulate the administration of radiotherapy according to a weekly schedule, to optimize treatment efficacy.",

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pages = "87--92",

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T1 - Circadian and circaseptan dependence of the beta-ATP peak of four different cancer cell cultures

T2 - Implications for chronoradiotherapy

AU - Ulmer, W.

AU - Cornelissen, G.

AU - Revilla, M.

AU - Siegelová, J.

AU - Dušek, J.

AU - Halberg, F.

PY - 2001

Y1 - 2001

N2 - The aim of the study was to examine the time-dependence of the beta-ATP peak of different tumor cells in vitro as a gauge of overall metabolism. In view of the large circaseptan-over-circadian prominence of the time-dependence of the beta-ATP peak, it is suggested to modulate the administration of radiotherapy according to a weekly schedule, to optimize treatment efficacy.

AB - The aim of the study was to examine the time-dependence of the beta-ATP peak of different tumor cells in vitro as a gauge of overall metabolism. In view of the large circaseptan-over-circadian prominence of the time-dependence of the beta-ATP peak, it is suggested to modulate the administration of radiotherapy according to a weekly schedule, to optimize treatment efficacy.

KW - Beta-ATP peak

KW - Cancer cell cultures

KW - Circadian and circaseptan rhythm

KW - Implications for chronoradiotherapy

UR - https://www.scopus.com/pages/publications/0035184935

UR - https://www.scopus.com/pages/publications/0035184935#tab=citedBy

M3 - Article

AN - SCOPUS:0035184935

SN - 1211-3395

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JO - Scripta Medica Facultatis Medicae Universitatis Brunensis Masarykianae

JF - Scripta Medica Facultatis Medicae Universitatis Brunensis Masarykianae

IS - 2

ER -

Circadian and circaseptan dependence of the beta-ATP peak of four different cancer cell cultures: Implications for chronoradiotherapy

Abstract

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