Chronomics reveal and quantify circadian rhythmic melatonin in duodenum of rats

K. Stebelova, M. Zeman, G. Cornélissen, G. Bubenik, R. Jozsa, R. Hardeland, B. Poeggeler, G. Huether, A. Olah, G. Nagy, V. Csernus, J. Kazsaki, W. Pan, K. Otsuka, E. E. Bakken, F. Halberg

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


A circadian rhythm is documented in duodenal melatonin in rats, peaking 16.8 hours after light onset. This component is more readily detected after log10-transformation of the data. It differs between male and female rats, females having a larger circadian amplitude and an earlier acrophase. The circadian rhythm in duodenal melatonin is also found to lead that of pineal melatonin. The results are qualified by the presence at the start of mapping of the second extremum of a double magnetic storm.

Original languageEnglish (US)
Pages (from-to)S209-S212
JournalBiomedicine and Pharmacotherapy
Issue numberSUPPL. 1
StatePublished - Oct 2005


  • Chronomics
  • Circadian
  • Duodenum
  • Melatonin
  • Rats


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