Chronomics

Circadian and circaseptan timing of radiotherapy, drugs, calories, perhaps nutriceuticals and beyond

Franz Halberg, Germaine Cornélissen, Zhengrong Wang, Chaomin Wan, Waldemar Ulmer, George Katinas, Ranjana Singh, R. K. Singh, Rajesh Kumar Singh, B. D. Gupta, R. B. Singh, Adarsh Kumar, Eugene Kanabrocki, Robert B. Sothern, Gundu Rao, Madan L B Bhatt, Madhu Srivastava, Gulshan Rai, Subhash Singh, Atanu Kumar Pati & 6 others Panchanan Nath, Francine Halberg, Julia Halberg, Othild Schwartzkopff, Earl Bakken, Shri Vishnu Kant Shastri

Research output: Contribution to journalReview article

49 Citations (Scopus)

Abstract

We suggest a putative benefit from timing nutriceuticals (substances that are both nutrients and pharmaceuticals) such as antioxidants for preventive or curative health care, based on the proven merits of timing nutrients, drugs, and other treatments, as documented, i.a., in India. The necessity of timing melatonin, a major antioxidant, is noted. A protocol to extend the scope of chronoradiotherapy awaits testing. Imaging in time by mapping rhythms and broader time structures, chronomes, for earliest diagnoses, for example detection of vascular disease risk, is recommended. The study of rhythms and broader chronomes leads to a dynamic functional genomics, guided by imaging in time of free radicals and antioxidants, amongst many other variables.

Original languageEnglish (US)
Pages (from-to)223-260
Number of pages38
JournalJournal of Experimental Therapeutics and Oncology
Volume3
Issue number5
DOIs
StatePublished - Sep 1 2003

Fingerprint

Dietary Supplements
Radiotherapy
Antioxidants
Pharmaceutical Preparations
Food
Melatonin
Genomics
Vascular Diseases
Free Radicals
Early Diagnosis
India
Delivery of Health Care
Therapeutics

Keywords

  • Chronome
  • Chronomics
  • Chronotherapy
  • Circadian
  • Circaseptan
  • Nutriceuticals

Cite this

Chronomics : Circadian and circaseptan timing of radiotherapy, drugs, calories, perhaps nutriceuticals and beyond. / Halberg, Franz; Cornélissen, Germaine; Wang, Zhengrong; Wan, Chaomin; Ulmer, Waldemar; Katinas, George; Singh, Ranjana; Singh, R. K.; Singh, Rajesh Kumar; Gupta, B. D.; Singh, R. B.; Kumar, Adarsh; Kanabrocki, Eugene; Sothern, Robert B.; Rao, Gundu; Bhatt, Madan L B; Srivastava, Madhu; Rai, Gulshan; Singh, Subhash; Pati, Atanu Kumar; Nath, Panchanan; Halberg, Francine; Halberg, Julia; Schwartzkopff, Othild; Bakken, Earl; Shastri, Shri Vishnu Kant.

In: Journal of Experimental Therapeutics and Oncology, Vol. 3, No. 5, 01.09.2003, p. 223-260.

Research output: Contribution to journalReview article

Halberg, F, Cornélissen, G, Wang, Z, Wan, C, Ulmer, W, Katinas, G, Singh, R, Singh, RK, Singh, RK, Gupta, BD, Singh, RB, Kumar, A, Kanabrocki, E, Sothern, RB, Rao, G, Bhatt, MLB, Srivastava, M, Rai, G, Singh, S, Pati, AK, Nath, P, Halberg, F, Halberg, J, Schwartzkopff, O, Bakken, E & Shastri, SVK 2003, 'Chronomics: Circadian and circaseptan timing of radiotherapy, drugs, calories, perhaps nutriceuticals and beyond', Journal of Experimental Therapeutics and Oncology, vol. 3, no. 5, pp. 223-260. https://doi.org/10.1111/j.1533-869X.2003.01097.x
Halberg, Franz ; Cornélissen, Germaine ; Wang, Zhengrong ; Wan, Chaomin ; Ulmer, Waldemar ; Katinas, George ; Singh, Ranjana ; Singh, R. K. ; Singh, Rajesh Kumar ; Gupta, B. D. ; Singh, R. B. ; Kumar, Adarsh ; Kanabrocki, Eugene ; Sothern, Robert B. ; Rao, Gundu ; Bhatt, Madan L B ; Srivastava, Madhu ; Rai, Gulshan ; Singh, Subhash ; Pati, Atanu Kumar ; Nath, Panchanan ; Halberg, Francine ; Halberg, Julia ; Schwartzkopff, Othild ; Bakken, Earl ; Shastri, Shri Vishnu Kant. / Chronomics : Circadian and circaseptan timing of radiotherapy, drugs, calories, perhaps nutriceuticals and beyond. In: Journal of Experimental Therapeutics and Oncology. 2003 ; Vol. 3, No. 5. pp. 223-260.
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AU - Wan, Chaomin

AU - Ulmer, Waldemar

AU - Katinas, George

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AU - Gupta, B. D.

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AU - Kumar, Adarsh

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AU - Sothern, Robert B.

AU - Rao, Gundu

AU - Bhatt, Madan L B

AU - Srivastava, Madhu

AU - Rai, Gulshan

AU - Singh, Subhash

AU - Pati, Atanu Kumar

AU - Nath, Panchanan

AU - Halberg, Francine

AU - Halberg, Julia

AU - Schwartzkopff, Othild

AU - Bakken, Earl

AU - Shastri, Shri Vishnu Kant

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