Chronobiology and chronomics honor Douglas Wilson. neither calories nor anything else are equal at breakfast and dinner or along other time scales

Germaine G Cornelissen-Guillaume, R. B. Singh, Othild Schwartzkopff, Franz Halberg

Research output: Contribution to journalReview articlepeer-review

Abstract

To honor Douglas Wilson, this paper reviews evidence for studying and quantifying rhythms as the indispensable control, whether to assess the effect of a fixed-calorie meal taken as breakfast or dinner, or to understand how human physiology and pathology may be affected by space-terrestrial weather. Since D. Wilson's work has dealt intensively with salivary hormonal determinations, we illustrate what can be learned from longitudinal series obtained in health or from a patient suffering from adynamic depression episodes recurring twice a year and lasting 2-3 months. The socially less unacceptable collection of serial salivary samples should be introduced more broadly into laboratory medicine for a more refined diagnosis and as a means to guide the optimization of any needed treatment by timing.

Original languageEnglish (US)
Pages (from-to)89-104
Number of pages16
JournalOpen Nutraceuticals Journal
Volume6
Issue numberSPEC.ISS.1
DOIs
StatePublished - 2013

Keywords

  • Chronobiology
  • Chronomics
  • Circadian stage-dependent response
  • Isocaloric meal
  • Relative weight loss
  • Salivary hormonal determinations

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