Chronic lung allograft dysfunction

Anupam Kumar, Puneet Singh Garcha

Research output: Contribution to journalReview articlepeer-review


Lung transplantation remains the only cure for selected patients with advanced irreversible lung diseases. More than 4000 lung transplants are performed worldwide annually. In the last two decades, significant advances have been made in this arena, the most impactful being a modest but improved survival of the recipients. Unfortunately majority of recipients still succumb to chronic lung allograft dysfunction (CLAD), and it remains the most common cause of death after the first year of transplantation. Below is a concise review of the current definition of CLAD, including the various phenotypes, and a brief discussion of the tools available for its diagnosis and management.

Original languageEnglish (US)
Pages (from-to)318-325
Number of pages8
JournalIndian Journal of Thoracic and Cardiovascular Surgery
StatePublished - Jul 2022
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2021, Indian Association of Cardiovascular-Thoracic Surgeons.


  • Chronic lung allograft dysfunction
  • Chronic rejection
  • Lung transplantation

PubMed: MeSH publication types

  • Journal Article
  • Review


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