TY - JOUR
T1 - Chronic Idiopathic Diarrhea
AU - Mintz, Eric D.
AU - Parsonnet, Julie
AU - Osterholm, Michael T.
AU - Afzalpurkar, Rekha G.
AU - Schiller, Lawrence R.
AU - Fordtran, John S.
PY - 1993/6/10
Y1 - 1993/6/10
N2 - To the Editor: As Afzalpurkar et al. (Dec. 24 issue)1 note, many features of the chronic idiopathic diarrhea they describe also occur in Brainerd diarrhea, a chronic diarrheal syndrome described after outbreaks in Minnesota and Illinois2,3. The authors suggest that the absence of four features – an identified point source, inflammation of colonic-biopsy specimens, fecal leukocytes, and intractable disease – distinguish their patients from patients with Brainerd diarrhea. We believe, however, that their criteria are unreliable. Point sources of Brainerd diarrhea are rarely identified, though cases of sporadic illness indistinguishable from Brainerd diarrhea have been reported in many…
AB - To the Editor: As Afzalpurkar et al. (Dec. 24 issue)1 note, many features of the chronic idiopathic diarrhea they describe also occur in Brainerd diarrhea, a chronic diarrheal syndrome described after outbreaks in Minnesota and Illinois2,3. The authors suggest that the absence of four features – an identified point source, inflammation of colonic-biopsy specimens, fecal leukocytes, and intractable disease – distinguish their patients from patients with Brainerd diarrhea. We believe, however, that their criteria are unreliable. Point sources of Brainerd diarrhea are rarely identified, though cases of sporadic illness indistinguishable from Brainerd diarrhea have been reported in many…
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U2 - 10.1056/NEJM199306103282314
DO - 10.1056/NEJM199306103282314
M3 - Letter
C2 - 8487837
AN - SCOPUS:0027288510
SN - 0028-4793
VL - 328
SP - 1713
EP - 1714
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 23
ER -