Chronic cavitary histoplasmosis. Failure of oral treatment with ketoconazole

C. A. Quinones; A. G. Reuben; R. J. Hamill; D. M. Musher; A. B. Gorin; G. A. Sarosi

doi:10.1378/chest.95.4.914

Chronic cavitary histoplasmosis. Failure of oral treatment with ketoconazole

C. A. Quinones, A. G. Reuben, R. J. Hamill, D. M. Musher, A. B. Gorin, G. A. Sarosi

Medicine - Veteran's Administration Medical Center

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Ketoconazole appears to be a safe drug in the treatment of chronic cavitary histoplasmosis. Primary failure and relapse have been described, requiring amphotericin B, even after long therapy with ketoconazole. Four typical cases are presented. We caution about such potential failures and stress the importance of close observation of patients begun on therapy with ketoconazole for chronic cavitary histoplasmosis.

Original language	English (US)
Pages (from-to)	914-916
Number of pages	3
Journal	CHEST
Volume	95
Issue number	4
DOIs	https://doi.org/10.1378/chest.95.4.914
State	Published - 1989

Publisher link

10.1378/chest.95.4.914

Find It

Find It at U of M Libraries

Cite this

@article{5f01ca4d26644076ada35fdb9da73546,

title = "Chronic cavitary histoplasmosis. Failure of oral treatment with ketoconazole",

abstract = "Ketoconazole appears to be a safe drug in the treatment of chronic cavitary histoplasmosis. Primary failure and relapse have been described, requiring amphotericin B, even after long therapy with ketoconazole. Four typical cases are presented. We caution about such potential failures and stress the importance of close observation of patients begun on therapy with ketoconazole for chronic cavitary histoplasmosis.",

author = "Quinones, {C. A.} and Reuben, {A. G.} and Hamill, {R. J.} and Musher, {D. M.} and Gorin, {A. B.} and Sarosi, {G. A.}",

year = "1989",

doi = "10.1378/chest.95.4.914",

language = "English (US)",

volume = "95",

pages = "914--916",

journal = "Diseases of the chest",

issn = "0012-3692",

publisher = "American College of Chest Physicians",

number = "4",

}

TY - JOUR

T1 - Chronic cavitary histoplasmosis. Failure of oral treatment with ketoconazole

AU - Quinones, C. A.

AU - Reuben, A. G.

AU - Hamill, R. J.

AU - Musher, D. M.

AU - Gorin, A. B.

AU - Sarosi, G. A.

PY - 1989

Y1 - 1989

N2 - Ketoconazole appears to be a safe drug in the treatment of chronic cavitary histoplasmosis. Primary failure and relapse have been described, requiring amphotericin B, even after long therapy with ketoconazole. Four typical cases are presented. We caution about such potential failures and stress the importance of close observation of patients begun on therapy with ketoconazole for chronic cavitary histoplasmosis.

AB - Ketoconazole appears to be a safe drug in the treatment of chronic cavitary histoplasmosis. Primary failure and relapse have been described, requiring amphotericin B, even after long therapy with ketoconazole. Four typical cases are presented. We caution about such potential failures and stress the importance of close observation of patients begun on therapy with ketoconazole for chronic cavitary histoplasmosis.

UR - http://www.scopus.com/inward/record.url?scp=0024561819&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024561819&partnerID=8YFLogxK

U2 - 10.1378/chest.95.4.914

DO - 10.1378/chest.95.4.914

M3 - Article

C2 - 2924624

AN - SCOPUS:0024561819

SN - 0012-3692

VL - 95

SP - 914

EP - 916

JO - Diseases of the chest

JF - Diseases of the chest

IS - 4

ER -

Chronic cavitary histoplasmosis. Failure of oral treatment with ketoconazole

Abstract

Publisher link

Find It

Other files and links

Fingerprint

Cite this