Chronic cavitary histoplasmosis. Failure of oral treatment with ketoconazole

C. A. Quinones, A. G. Reuben, R. J. Hamill, D. M. Musher, A. B. Gorin, G. A. Sarosi

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Ketoconazole appears to be a safe drug in the treatment of chronic cavitary histoplasmosis. Primary failure and relapse have been described, requiring amphotericin B, even after long therapy with ketoconazole. Four typical cases are presented. We caution about such potential failures and stress the importance of close observation of patients begun on therapy with ketoconazole for chronic cavitary histoplasmosis.

Original languageEnglish (US)
Pages (from-to)914-916
Number of pages3
Issue number4
StatePublished - 1989
Externally publishedYes


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