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Chromosome capture: Take me to your kinetochore

Research output: Contribution to journal › Short survey › peer-review

Abstract

To form a proper mitotic spindle, all kinetochores must capture at least one microtubule plus end. A new computational modeling study shows that a search-and-capture mechanism based on spatially unbiased microtubule dynamic instability is too slow to account for the experimentally observed rate of chromosome capture.

Original languageEnglish (US)
Pages (from-to)R328-R330
JournalCurrent Biology
Volume15
Issue number9
DOIs
StatePublished - May 10 2005

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