Chromosomal assignments for the equine AMPK family genes

P. K. Dranchak, K. J. Ekenstedt, S. J. Valberg, B. P. Chowdhary, T. Raudsepp, J. R. Mickelson

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

5′-AMP-activated protein kinase (AMPK), comprised of a catalytic α-subunit and non-catalytic β- and γ-subunits, plays a pivotal role in the regulation of cellular energy homeostasis. 1The PRKAA1, PRKAA2, PRKAB1, PRKAB2, PRKAG1, PRKAG2 and PRKAG3 genes encode the seven possible subunits of a functional mammalian AMPK heterotrimer. We derived over 70% of the coding sequence of each equine AMPK subunit gene and determined their chromosomal locations by radiation hybrid mapping and fluorescence in situ hybridization (FISH).

Original languageEnglish (US)
Pages (from-to)293-294
Number of pages2
JournalAnimal Genetics
Volume37
Issue number3
DOIs
StatePublished - Jun 2006

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