Chromatin Compaction at Hox Loci: A Polycomb Tale beyond Histone Tails

Research output: Contribution to journalShort survey

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Abstract

A new study in this issue of Molecular Cell (Eskeland et al., 2010) implicates Polycomb repressive complex 1 (PRC1) in compacting Hox gene chromatin in mouse embryonic stem cells and suggests that compaction, rather than histone tail ubiquitylation, confers Hox gene silencing.

Original languageEnglish (US)
Pages (from-to)321-322
Number of pages2
JournalMolecular Cell
Volume38
Issue number3
DOIs
StatePublished - May 14 2010

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