Chloramphenicol: Effects on mouse myeloma cells in tissue culture

Boyd K. Hartman, Olive S. Pettengill, George D. Sorenson

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Within 36 hours of being administered, chloramphenicol (50 micrograms per milliliter) inhibits by 50 percent the rate of protein synthesis in mouse myeloma cells grown in suspension culture. Although there is a decrease in the amount of globulin synthesized, the rate of synthesis per cell is unchanged; the observed decrease is traced to the inhibition of cell proliferation caused by chloramphenicol.

Original languageEnglish (US)
Pages (from-to)297-298
Number of pages2
JournalScience
Volume165
Issue number3890
DOIs
StatePublished - Jan 1 1969

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    Hartman, B. K., Pettengill, O. S., & Sorenson, G. D. (1969). Chloramphenicol: Effects on mouse myeloma cells in tissue culture. Science, 165(3890), 297-298. https://doi.org/10.1126/science.165.3890.297