Childhood obesity patterns and relation to middle-age sleep apnoea risk: The Bogalusa heart study

L. A. Bazzano, T. Hu, S. M. Bertisch, L. Yao, E. W. Harville, J. Gustat, W. Chen, L. S. Webber, T. Shu, S. Redline

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Background: Obese adults have a higher risk of obstructive sleep apnoea (OSA); however, the relationship between childhood obesity and adult OSA risk is unclear. Objectives This study aimed to examine overweight/obesity (OW) in childhood and risk of OSA in middle age. Methods: Childhood OW status was classified as never OW, weight cycling, persistent OW and incident OW. After 35 years of follow-up, high risk for OSA was determined by a positive score in ≥2 domains on the Berlin Questionnaire with obesity removed from scoring. Results: At initial assessment, mean (SD) age was 9.9 (2.9) years, and 23.9% were OW. Overall, 25.7% had scores indicating a high risk for OSA. Compared with participants who were never OW, those with persistent OW and incident OW were 1.36 (95%CI: 1.04-1.77) and 1.47 (1.11-1.96) times more likely to be high risk for OSA, after adjustment for multiple risk factors and adult OW status. Participants with an OW duration of 1-4 years, 5-8 years, and 8+ years were 0.96 (0.44-2.09), 1.20 (0.70-2.04) and 1.52 (1.22-1.90) times more likely to be high risk for OSA compared with those who were never OW (P for trend: 0.0002). Conclusions: These results suggest that childhood OW is associated with a high risk of OSA in middle age.

Original languageEnglish (US)
Pages (from-to)535-542
Number of pages8
JournalPediatric Obesity
Volume11
Issue number6
DOIs
StatePublished - Dec 1 2016

Bibliographical note

Funding Information:
The Bogalusa Heart Study is supported by grants R01 ES021724 from the National Institute of Environmental Health Sciences, R01 AG016592 from the National Institute on Aging and R01 AG041200 from the National Institute on Aging.

Publisher Copyright:
© 2016 World Obesity Federation.

Keywords

  • Childhood obesity
  • Cohort study
  • Obesity duration
  • Obstructive sleep apnoea

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