Childhood and Life-Course Socioeconomic Position and Cognitive Function in the Adult Population of the Hispanic Community Health Study/Study of Latinos

Paola Filigrana, Jee Young Moon, Linda C. Gallo, Lindsay Fernández-Rhodes, Krista M. Perreira, Martha L. Daviglus, Bharat Thyagarajan, Olga L. Garcia-Bedoya, Jianwen Cai, Richard B. Lipton, Robert C. Kaplan, Hector M. Gonzalez, Carmen R. Isasi

Research output: Contribution to journalArticlepeer-review

Abstract

The Hispanic/Latino population experiences socioeconomic adversities across the lifespan and is at greater risk of cognitive impairment, yet little is known about the role of life-course socioeconomic position (SEP) in cognitive function in this population. Using baseline data (2008-2011) from adults (aged 45-74 years) of the Hispanic Community Health Study/Study of Latinos, we assessed the association between childhood SEP and socioeconomic mobility with cognitive function, and whether this association was mediated by midlife SEP. Childhood SEP was assessed using parental education. An index combining participants' education and household income represented midlife SEP. Socioeconomic mobility was categorized as stable low, downward or upward mobility, and stable high-SEP. Cognitive function measures were modeled using survey linear regression with inverse-probability weighting, accounting for covariates. We used mediation analysis to estimate the indirect effect of childhood SEP on cognition through midlife SEP. High childhood SEP was associated with global cognition in adulthood (coefficient for parental education beyond high school vs. less than high school = 0.26, 95% confidence interval: 0.15, 0.37). This association was partially mediated through midlife SEP (indirect effect coefficient = 0.16, 95% confidence interval: 0.15, 0.18). Low SEP through the life course was associated with the lowest cognitive function. This study provides evidence that life-course SEP influences cognitive performance in adulthood.

Original languageEnglish (US)
Pages (from-to)2006-2017
Number of pages12
JournalAmerican journal of epidemiology
Volume192
Issue number12
DOIs
StatePublished - Dec 1 2023

Bibliographical note

Publisher Copyright:
© 2023 The Author(s).

Keywords

  • adults
  • cognition
  • Hispanics
  • Latinos
  • life course
  • social mobility
  • socioeconomic position

PubMed: MeSH publication types

  • Journal Article
  • Research Support, N.I.H., Extramural

Fingerprint

Dive into the research topics of 'Childhood and Life-Course Socioeconomic Position and Cognitive Function in the Adult Population of the Hispanic Community Health Study/Study of Latinos'. Together they form a unique fingerprint.

Cite this