Chemoprevention of lung tumorigenesis by intranasally administered diindolylmethane in A/J mice

Medicine and Dentistry

• Chemoprophylaxis 100%
• Lung 100%
• Neoplasm 100%
• Carcinogenesis 100%
• Lung Cancer 75%
• Lung Tumor 75%
• Chemoprevention 50%
• Intranasal Drug Administration 50%
• Clinical Trial 25%
• Low Drug Dose 25%
• In Vitro 25%
• Cell Signaling Pathway 25%
• Side Effect 25%
• Phosphoinositide 3-Kinase 25%
• Bioavailability 25%
• Akt Signaling 25%
• 4 (Methylnitrosamino) 1 (3 Pyridyl) 1 Butanone 25%
• Carcinogen 25%

Keyphrases

• Chemoprevention 100%
• Lung Tumorigenesis 100%
• Diindolylmethane 100%
• Bio-response 71%
• Lung Cancer 42%
• Lung Tumor 42%
• Tumor 28%
• Cancer Chemoprevention 28%
• Intranasal Instillation 28%
• Clinical Trials 14%
• Chemopreventive 14%
• Two-dose 14%
• High Risk 14%
• Intranasal Delivery 14%
• Direct Delivery 14%
• Carcinogen 14%
• In Vitro Model 14%
• Antiproliferative Activity 14%
• 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone 14%
• Minimal Impact 14%
• Apoptotic Effect 14%
• Inhibitory Activity 14%
• Bronchial Epithelial Cells 14%
• Tumor Volume 14%
• Large Tumors 14%
• AKT Pathway 14%
• Tumor multiplicity 14%
• Chemoprevention Trial 14%
• In Vivo Dose 14%
• Pulmonary Tissue 14%
• Phosphatidylinositol 3-kinase/Akt Signaling 14%
• In Vivo Bioavailability 14%
• Immortalized Cell 14%

Pharmacology, Toxicology and Pharmaceutical Science

• A J Mouse 100%
• Neoplasm 100%
• Carcinogenesis 100%
• Lung Tumor 75%
• Lung Cancer 75%
• NNK 50%
• Carcinogen 25%
• Clinical Trial 25%
• Chemopreventive Agents 25%
• Side Effect 25%
• Phosphatidylinositol 3 Kinase 25%
• 4 (Methylnitrosamino) 1 (3 Pyridyl) 1 Butanone 25%
• Bioavailability 25%
• Protein Kinase B 25%