Characterizing macrophage diversity in metastasis-bearing lungs reveals a lipid-associated macrophage subset

Keyphrases

• Lung 100%
• Metastasis 100%
• Macrophages 100%
• Lipid-laden Macrophages 100%
• Macrophage Subsets 100%
• Macrophage Diversity 100%
• Immunosuppression 40%
• Single-cell RNA Sequencing (scRNA-seq) 40%
• Lipid Metabolism 40%
• Mammary Tumor 40%
• Extracellular Matrix Remodeling 40%
• Lung Metastasis 40%
• Antigen Presentation 20%
• Phagocytosis 20%
• Metastatic Progression 20%
• Alveolar Macrophages 20%
• Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) 20%
• Interferon Signaling 20%
• Tumor-bearing Mice 20%
• Cyclin-dependent Kinase 1 (CDK1) 20%
• Gene Differential Expression 20%
• LGALS3 20%
• Interferon-stimulated Gene 15 (ISG15) 20%
• Nontumor 20%
• Immune Parameters 20%
• Macrophage Heterogeneity 20%
• STMN1 20%
• CD74 20%
• IFITM3 20%
• Siglec-F 20%
• Macrophage Markers 20%
• Metastatic Lesions 20%

Immunology and Microbiology

• Macrophage 100%
• Macrophage Subset 100%
• Immunosuppression 25%
• RNA Sequence 25%
• Extracellular Matrix 25%
• Lipid Metabolism 25%
• Interferon Type I 12%
• Alveolar Macrophage 12%
• Immunocompetent Cell 12%
• CD74 12%
• Sialic Acid Binding Immunoglobulin Like Lectin 12%
• Antigen Presentation 12%
• Phagocytosis 12%
• Cell Cycle 12%

Biochemistry, Genetics and Molecular Biology

• Lipid 100%
• Macrophage 100%
• Lipid Metabolism 20%
• RNA Sequence 20%
• CD74 10%
• Siglec 10%
• Antigen Presentation 10%
• Immunocompetent Cell 10%
• Cell Cycle 10%
• Phagocytosis 10%
• Alveolar Macrophage 10%
• Interferon 10%