Characterizationf of autoxidation products of retinoic acid

  • A. R. Oyler
  • , M. G. Motto
  • , R. E. Naldi
  • , K. L. Facchine
  • , P. F. Hamburg
  • , D. J. Burinsky
  • , R. Dunphy
  • , M. L. Cotter

Research output: Contribution to journalArticlepeer-review

38 Scopus citations

Abstract

Retinoic acid underwent autoxidation in 90% ethanol at 25-85.5 °C to give epoxides, dioxetanes, an endoperoxide, and double-bond cleavage products. The majority of these products appear to have resulted from the initial direct oxidation of the olefinic carbons rather than from the expected allylic α oxidation process.

Original languageEnglish (US)
Pages (from-to)7679-7694
Number of pages16
JournalTetrahedron
Volume45
Issue number24
DOIs
StatePublished - 1989

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