Characterization of three plasmid deoxyribonucleic acid molecules in a strain of Streptococcus faecalis: identification of a plasmid determining erythromycin resistance

D. B. Clewell, Y. Yagi, G. M. Dunny, S. K. Schultz

Research output: Contribution to journalArticlepeer-review

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Abstract

Three plasmids designated α, β, and γ, distinguishable by their molecular weights (6, 17, and 34 million, respectively) were isolated from S. faecalis strain DS 5 (ATCC 14508). Derivatives of this strain 'cured' for erythromycin resistance lacked the β plasmid. In the parent strain the β plasmid was estimated to be present to the extent of one to two copies per chromosomal genome equivalent whereas the α and γ plasmids were about nine and five copies, respectively.

Original languageEnglish (US)
Pages (from-to)283-289
Number of pages7
JournalJournal of Bacteriology
Volume117
Issue number1
StatePublished - Jan 1 1974

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