TY - JOUR
T1 - Characterization of canine adenovirus type 1 isolated from American black bears.
AU - Whetstone, C. A.
AU - Draayer, H.
AU - Collins, J. E.
PY - 1988/6
Y1 - 1988/6
N2 - Viruses recovered from tissues taken at necropsy from American black bears were examined by use of immunofluorescence with polyclonal and monoclonal antibodies, virus neutralization with monoclonal antibodies, and restriction endonuclease analyses of the viral genomes. With these techniques, viruses were determined to be canine adenovirus type 1. Seronegative dogs that were inoculated with the virus had clinical signs typical of infectious canine hepatitis, suggesting that the virus, which was virulent for bears, was not a vaccinal strain, but a wild strain of canine adenovirus type 1.
AB - Viruses recovered from tissues taken at necropsy from American black bears were examined by use of immunofluorescence with polyclonal and monoclonal antibodies, virus neutralization with monoclonal antibodies, and restriction endonuclease analyses of the viral genomes. With these techniques, viruses were determined to be canine adenovirus type 1. Seronegative dogs that were inoculated with the virus had clinical signs typical of infectious canine hepatitis, suggesting that the virus, which was virulent for bears, was not a vaccinal strain, but a wild strain of canine adenovirus type 1.
UR - https://www.scopus.com/pages/publications/0024027055
UR - https://www.scopus.com/inward/citedby.url?scp=0024027055&partnerID=8YFLogxK
M3 - Article
C2 - 2840839
AN - SCOPUS:0024027055
SN - 0002-9645
VL - 49
SP - 778
EP - 780
JO - American journal of veterinary research
JF - American journal of veterinary research
IS - 6
ER -
