Characterization of binding mode of imatinib to human α ₁-acid glycoprotein

Keyphrases

• Glycoprotein 100%
• Imatinib 100%
• Binding Mode 100%
• Tyrosine Kinase Inhibitor 20%
• High Affinity 20%
• Genetic Variants 20%
• Chronic Myeloid Leukemia 20%
• Gastrointestinal Stromal Tumor 20%
• Low Affinity 20%
• Kinase Target 20%
• Binding Studies 20%
• X-ray Structure 20%
• Plasma Protein Binding 20%
• Extended Conformation 20%
• Quinone Reductase 20%
• Spectral Changes 20%
• Molecular Modeling Calculation 20%
• High-affinity Interaction 20%

Biochemistry, Genetics and Molecular Biology

• Imatinib 100%
• Glycoprotein 100%
• Conformation 40%
• X Ray 20%
• Genetic Divergence 20%
• Tyrosine Kinase Inhibitor 20%
• Reductase 20%
• Molecular Modeling 20%
• Binding Study 20%
• Myeloid 20%
• Molecular Model 20%
• Plasma Protein Binding 20%
• Oxidoreductase 20%
• Phosphotransferase 20%
• Kinase 20%