Changes in the pharmacokinetics of cyclosporine and three of its metabolites in renal transplant patients early in the posttransplant period

W. M. Awni; B. Kasiske; K. Heim-Duthoy; M. Rose; V. K. Rao; P. Bloom; A. Ney; J. Andrisevic; M. Odland; R. C. Andersen

Changes in the pharmacokinetics of cyclosporine and three of its metabolites in renal transplant patients early in the posttransplant period

W. M. Awni, B. Kasiske, K. Heim-Duthoy, M. Rose, V. K. Rao, P. Bloom, A. Ney, J. Andrisevic, M. Odland, R. C. Andersen

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Abstract

In this article, we report our preliminary analysis of the results of a pharmacokinetic study of cyclosporine and three of its metabolites, two hydroxylated (M1 and M17) and one demethylated (M21) in renal transplant patients. Changes in the pharmacokinetic parameters of CsA, M1, M17, and M21 were examined over time at 1 week, 3 weeks, and 3 months after the start of CsA therapy.

Original language	English (US)
Pages (from-to)	623-624
Number of pages	2
Journal	Transplantation proceedings
Volume	20
Issue number	2 SUPPL. 2
State	Published - 1988
Externally published	Yes

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title = "Changes in the pharmacokinetics of cyclosporine and three of its metabolites in renal transplant patients early in the posttransplant period",

abstract = "In this article, we report our preliminary analysis of the results of a pharmacokinetic study of cyclosporine and three of its metabolites, two hydroxylated (M1 and M17) and one demethylated (M21) in renal transplant patients. Changes in the pharmacokinetic parameters of CsA, M1, M17, and M21 were examined over time at 1 week, 3 weeks, and 3 months after the start of CsA therapy.",

author = "Awni, \{W. M.\} and B. Kasiske and K. Heim-Duthoy and M. Rose and Rao, \{V. K.\} and P. Bloom and A. Ney and J. Andrisevic and M. Odland and Andersen, \{R. C.\}",

year = "1988",

language = "English (US)",

volume = "20",

pages = "623--624",

journal = "Transplantation proceedings",

issn = "0041-1345",

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number = "2 SUPPL. 2",

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TY - JOUR

T1 - Changes in the pharmacokinetics of cyclosporine and three of its metabolites in renal transplant patients early in the posttransplant period

AU - Awni, W. M.

AU - Kasiske, B.

AU - Heim-Duthoy, K.

AU - Rose, M.

AU - Rao, V. K.

AU - Bloom, P.

AU - Ney, A.

AU - Andrisevic, J.

AU - Odland, M.

AU - Andersen, R. C.

PY - 1988

Y1 - 1988

N2 - In this article, we report our preliminary analysis of the results of a pharmacokinetic study of cyclosporine and three of its metabolites, two hydroxylated (M1 and M17) and one demethylated (M21) in renal transplant patients. Changes in the pharmacokinetic parameters of CsA, M1, M17, and M21 were examined over time at 1 week, 3 weeks, and 3 months after the start of CsA therapy.

AB - In this article, we report our preliminary analysis of the results of a pharmacokinetic study of cyclosporine and three of its metabolites, two hydroxylated (M1 and M17) and one demethylated (M21) in renal transplant patients. Changes in the pharmacokinetic parameters of CsA, M1, M17, and M21 were examined over time at 1 week, 3 weeks, and 3 months after the start of CsA therapy.

UR - https://www.scopus.com/pages/publications/0023898969

UR - https://www.scopus.com/inward/citedby.url?scp=0023898969&partnerID=8YFLogxK

M3 - Article

C2 - 3284111

AN - SCOPUS:0023898969

SN - 0041-1345

VL - 20

SP - 623

EP - 624

JO - Transplantation proceedings

JF - Transplantation proceedings

IS - 2 SUPPL. 2

ER -

Changes in the pharmacokinetics of cyclosporine and three of its metabolites in renal transplant patients early in the posttransplant period

Abstract

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