Changes in ribonuclease activity during development of the mosquito, Aedes aegypti

Mary Ann Fritz, Phyllis G. Hotchkin, Ann Marie Fallon

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


1. 1. In the mosquito Aedes aegypti, quantitative and qualitative changes have been detected in ribonuclease activity during development. 2. 2. Ribonuclease activity is particularly high in extracts from larvae, relative to that in extracts from pupae or adults. 3. 3. Larval extract is enriched for a ribonuclease that is heat-labile, has an alkaline pH optimum, and is extremely sensitive to the divalent cation, manganese. 4. 4. Extract from adult females is enriched for a heat-stable component that has an acidic pH optimum and is more active at 56 than at 30°C. 5. 5. Throughout the vitellogenic cycle, no major changes in ribonuclease activity were detected in fat body extracts.

Original languageEnglish (US)
Pages (from-to)355-361
Number of pages7
JournalComparative Biochemistry and Physiology -- Part B: Biochemistry and
Issue number3
StatePublished - 1986

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