Cervical cancer

Jovana Y. Martin, Britt K. Erickson, Warner K. Huh

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations


Worldwide, approximately 493,000 women are diagnosed with cervical cancer yearly. Infection with high risk Human Papillomavirus (HPV) is necessary for the development of cervical cancer. Risk factors including sexual history and tobacco affect HPV acquisition and persistence. Since the implementation of cervical cancer screening programs, morbidity and mortality from cervical cancer have decreased. Hysterectomy and chemoradiation therapy are the mainstays of cervical cancer treatment. We wished to conduct a review of cervical cancer using evidence based medicine. Clinical questions relevant to the clinical scenario were developed using the evidence based medicine format, PICO (Population, Intervention, Comparison, and Outcomes). We searched the EMBASE, CINAHL, PubMed, Medline, and Cochrane Databases as well as performed a manual search of references for each question. In this review we will discuss cervical cancer risk factors, cervical cancer screening including cytology and HPV testing, and the primary treatment of cervical cancer.

Original languageEnglish (US)
Title of host publicationEvidence-based Obstetrics and Gynecology
Number of pages8
ISBN (Electronic)9781119072980
StatePublished - 2018

Bibliographical note

Publisher Copyright:
© 2019 John Wiley & Sons Ltd.


  • Cervical cancer
  • Cervical cancer Screening
  • Cervical intraepithelial neoplasia (CIN)
  • Human Papillomavirus (HPV)
  • Papanicolaou smear (Pap Smear)
  • Radical hysterectomy Radiation therapy


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