Worldwide, approximately 493,000 women are diagnosed with cervical cancer yearly. Infection with high risk Human Papillomavirus (HPV) is necessary for the development of cervical cancer. Risk factors including sexual history and tobacco affect HPV acquisition and persistence. Since the implementation of cervical cancer screening programs, morbidity and mortality from cervical cancer have decreased. Hysterectomy and chemoradiation therapy are the mainstays of cervical cancer treatment. We wished to conduct a review of cervical cancer using evidence based medicine. Clinical questions relevant to the clinical scenario were developed using the evidence based medicine format, PICO (Population, Intervention, Comparison, and Outcomes). We searched the EMBASE, CINAHL, PubMed, Medline, and Cochrane Databases as well as performed a manual search of references for each question. In this review we will discuss cervical cancer risk factors, cervical cancer screening including cytology and HPV testing, and the primary treatment of cervical cancer.
|Original language||English (US)|
|Title of host publication||Evidence-based Obstetrics and Gynecology|
|Number of pages||8|
|ISBN (Print)||9781119072959; 9781119072928; 9781444334333|
|State||Published - 2018|
Bibliographical notePublisher Copyright:
© 2019 John Wiley & Sons Ltd.
- Cervical cancer
- Cervical cancer Screening
- Cervical intraepithelial neoplasia (CIN)
- Human Papillomavirus (HPV)
- Papanicolaou smear (Pap Smear)
- Radical hysterectomy Radiation therapy