A range of N-tosylaziridines is cleaved with NaN3, H2O, MeOH to synthesize vicinal azidoamines, aminols and amino ethers in good to excellent yields catalyzed by ceric ammonium nitrate and used in solution phase library synthesis.
Bibliographical noteFunding Information:
Two of us, C.N. and S.S.S., are thankful to CSIR, New Delhi for financial assistance.
Copyright 2008 Elsevier B.V., All rights reserved.
- Ceric ammonium nitrate
- N-substituted aziridines
- Solution phase library
- Vicinal azidoamines