Cerebrovascular disease in the era of left ventricular assist devices with continuous flow: Risk factors, diagnosis, and treatment

Joshua Z. Willey, Ryan T. Demmer, Hiroo Takayama, Paolo C. Colombo, Ronald M. Lazar

Research output: Contribution to journalEditorialpeer-review

60 Scopus citations

Abstract

Cerebral infarction and hemorrhage are among the principal sources of morbidity and mortality associated with mechanical circulatory support. There has been particular concern with the recently reported increased rate of device thrombosis in continuous-flow left ventricular assist devices. The neurologic management of stroke among these patients has limited data to inform current clinical practices. In this investigation we review the available literature on stroke in patients with continuous-flow left ventricular assist devices, with a focus on treatment algorithms in the acute setting and for secondary stroke prevention.

Original languageEnglish (US)
Pages (from-to)878-887
Number of pages10
JournalJournal of Heart and Lung Transplantation
Volume33
Issue number9
DOIs
StatePublished - Sep 2014

Bibliographical note

Funding Information:
This study was supported by a grant from the National Institute of Neurological Disorders and Stroke (K23 NS 073104 to J.Z.W.). P.C.C. and R.M.L. contributed equally to this manuscript.

Keywords

  • acute stroke
  • epidemiology
  • intracerebral hemorrhage
  • ischemic stroke
  • left ventricular assist device
  • stroke prevention

Fingerprint

Dive into the research topics of 'Cerebrovascular disease in the era of left ventricular assist devices with continuous flow: Risk factors, diagnosis, and treatment'. Together they form a unique fingerprint.

Cite this