Central effects of neuropeptides on ventilation in the rat

D. E. Niewoehner, A. S. Levine, J. E. Morley

Research output: Contribution to journalArticlepeer-review

2 Scopus citations
Original languageEnglish (US)
Pages (from-to)774A
JournalClinical Research
Issue number4
StatePublished - 1981

Bibliographical note

Funding Information:
The peptides were obtained commercially: bombesin (0.1-10.0 /xg ICV: Sigma Chemical Company, St. Louis, MO); neurotensin (10/xg ICV: Vega Chemicals, Reno, NV); thyrotropin releasing hormone (TRH 0.1-10.0 /xg ICV: Boehringer-Mannheim, Indianapolis, IN); somatostatin (10 /xg ICV: Beckman, Palo Alto, CA); pyro-glutamyl histidyl proline (acid TRH 1.0-10.0 tzg ICV: Vega Biochemicals, Tuscon, AZ); substance P (10/zg ICV: Vega Biochemicals, Tucson, AZ); calcitonin (0.02-2.0 units ICV: Armour Pharmaceutical Company, Phoenix, AZ), histidyl-proline di-latopiperazine (cHis-Pro 10 /zg ICV: Vega Biochemicals Company, Tucson, AZ). All peptides were administered ICV in five microliters of physiological saline. Control animals ~This work was supported by the Veterans Administration Research Service. 2Requests for reprints should be addressed to John E. Morley, M.B., B. Ch., Minneapolis VA Medical Center, Minneapolis, MN 55417.

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