Cellulose Acetate Impressions Of The Ocular Surface: Dry Eye States

J. Daniel Nelson, Virginia R. Havener, J. Douglas Cameron

Research output: Contribution to journalArticlepeer-review

267 Scopus citations

Abstract

Cellulose acetate impressions of the ocular surface were obtained for normal eyes, eyes with blepharoconjunctivitis, eyes with keratoconjunctivitis sicca, and eyes with primary ocular surface disease. Normal eyes and eyes with blepharoconjunctivitis had morphologically normal epithelium and goblet cells on the bulbar and palpebral ocular surfaces. Eyes with primary ocular surface disease had abnormal ocular surface impressions (decreased, abnormal, or absent goblet cells with abnormal epithelial cells) on both the bulbar and palpebral ocular surfaces. Conversely, eyes with keratoconjunctivitis sicca had substantial abnormalities of the epithelium and goblet cells only on the bulbar ocular surface, suggesting an environmental role in this disease process.

Original languageEnglish (US)
Pages (from-to)1869-1872
Number of pages4
JournalArchives of Ophthalmology
Volume101
Issue number12
DOIs
StatePublished - Dec 1983

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